How does Perlane® work?
Just like Restylane, Perlane adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).
Like Restylane, Perlane is a clear gel formulation of hyaluronic acid that is specifically formulated to add volume like your body's own hyaluronic acid.
What makes Perlane different is the average size of the particles and the depth of injection. On average, the gel particles in Perlane are larger than those in Restylane, which makes Perlane a good choice for wrinkles that benefit from a deeper injection into the skin.
In three clinical studies of 150 patients each, on average 70% of patients maintained improvement for six months after just one Perlane treatment.
Everyone is different. Work with your healthcare professional to determine how much Perlane® you may need to fully correct the lines from your nose to the corners of your mouth (nasolabial folds). Your healthcare professional may refer to this as "full correction," so ask for it by name.
During your consultation, your healthcare professional will decide which product is right for you.
Get a more comfortable lift with Perlane-L
If you want a more youthful appearance, but you’re concerned about the potential discomfort from treatment, you can get beautiful results and a more comfortable Perlane experience.
By combining lidocaine with Perlane® and Perlane-L help reduce discomfort during and after treatment.
In clinical studies evaluating the Restylane family of products:
- 95% of patients reported significantly less pain during treatment with Perlane-L vs. Perlane
- Patients continued to experience less discomfort for up to one hour after treatment
Perlane-L can be used to add volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). This product is not approved for use in lip enhancement.
Perlane-L should not be used by anyone with a known allergy to lidocaine.
Safety Considerations for the Restylane® products
Products in the Restylane family should not be used by people with previous bad allergies, particularly to microorganisms known as gram-positive bacteria, or by people with serious allergies to drugs that have previously required in-hospital treatment. These products should not be used by people with bleeding disorders. Products should not be injected anywhere except the skin, just under the skin (Perlane and Perlane-L only), or in the lips (Restylane only). Restylane-L and Perlane-L should not be used by anyone with a known allergy to lidocaine.
Use at the site of skin sores, pimples, rashes, hives, cysts, or infection should be postponed until healing is complete. In these instances, product use could delay healing or make your skin problems worse. After treatment, you might have some swelling, redness, pain, bruising, or tenderness. These are typically mild in severity and normally last less than 7 days in nasolabial folds and less than 14 days in lips. Swelling may be more likely in patients under 36 years, and bruising may be more likely in patients over 35 years. Rarely, the doctor may inject into a blood vessel, which can damage the skin. Although rare, red or swollen small bumps may occur. If you have had facial cold sores before, an injection can cause an outbreak. To avoid bruising and bleeding, you should not use the products if you have recently used drugs that thin your blood or prevent clotting. Products should not be used during pregnancy, when breastfeeding, or in patients under 18 years for nasolabial folds.
Treatment volume should be limited to 6.0 mL in wrinkles and folds, such as nasolabial folds, and limited to 1.5 mL per lip (Restylane only), as greater amounts significantly increase moderate and severe injection site reactions. The safety or effectiveness of treatment in areas other than nasolabial folds and lips (Restylane only) has not been established in controlled clinical studies.
The Restylane family of products is available only through a licensed practitioner.